Yashoda Hospitals Performs Life-Saving Haploidentical Stem Cell Transplant for 10-Month-Old with Rare Bone Marrow Failure

Hyderabad, 25th February 2026: Yashoda Hospitals has once again demonstrated its clinical excellence by giving a new lease of life to a 10-month-old boy suffering from a rare, life-threatening bone marrow failure disorder — Congenital Amegakaryocytic Thrombocytopenia (CAMT) — through a state-of-the-art haploidentical stem cell transplantation at its Somajiguda unit.

The infant, Master M. Khadar Armaan, son of Mulla Khaja and Reshme from Nandavaram, Kurnool district, was admitted to Yashoda Hospitals – Somajiguda on December 26, 2025, with persistently low platelet counts. During hospitalization, the child experienced an aspiration episode while feeding, leading to sudden respiratory distress, hypoxia, and bradycardia. He was immediately intubated and placed on mechanical ventilation in the Pediatric Intensive Care Unit for four days.

After comprehensive clinical and laboratory evaluation, doctors diagnosed the child with Congenital Amegakaryocytic Thrombocytopenia, a rare inherited bone marrow failure disorder characterized by severe thrombocytopenia and high bleeding risk. The only curative treatment for this condition is allogeneic hematopoietic stem cell transplantation.

Expert Medical Intervention

Speaking on the occasion, Dr. Ashok Kumar Pillai, Senior Hemato-Oncologist & Bone Marrow Transplant Specialist at Yashoda Hospitals – Somajiguda, said Since a fully matched donor was unavailable, we evaluated the child’s father as a potential donor. He was found suitable, and we proceeded with a haploidentical stem cell transplantation using paternal stem cells.”

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The transplant was successfully performed on January 8, 2026. Following the procedure, the child showed steady recovery under continuous expert monitoring and critical care support. As the platelet count gradually improved, ventilatory support was discontinued. The child was discharged after achieving medical stability, marking a successful transplant outcome.

Importance of Early Diagnosis & Advanced Care

Dr. S. Prashanth Reddy, Unit Head, Yashoda Hospitals – Somajiguda, stated “This case underscores the importance of early diagnosis, timely access to advanced transplant facilities, and coordinated multidisciplinary care in managing rare pediatric hematological disorders. The successful outcome reflects the combined efforts of Hematology & Transplantation, Pediatrics, Transfusion Medicine, Nursing, and Hospital Management.”

He further emphasized that many childhood blood disorders once considered fatal can now be cured with modern medical advancements, and such cases raise public awareness about early diagnosis and appropriate treatment.

About Haploidentical Stem Cell Transplantation

Haploidentical transplantation allows a half-matched family donor, typically a parent, to donate stem cells when a fully matched donor is not available. This advanced procedure significantly increases donor availability and offers a lifesaving option for patients with rare and critical blood disorders.